Marike Harmsen began drawing at an early age. After being admitted to the art academy in Kampen, she decided to study medicine instead. As a doctor specialising in rehabilitation medicine, she likes to intersperse her work with drawing and painting. She has further developed her technique as an autodidact. She has taken courses in Nijmegen and Den Bosch. She makes use of various techniques in her work, which is both figurative and abstract.